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1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-[(4-methoxyphenyl)sulfonyl]piperazine
- Development stage
- Unknown
- Modality
- Small Molecules
01
Overview
This compound is a synthetic small molecule belonging to the benzenesulfonamide class. It features a piperazine core substituted with both a (2,3-dihydrobenzo[1,4]dioxin)-6-sulfonyl group and a (4-methoxyphenyl)sulfonyl group. The compound has been identified as an experimental ligand for the NMDA receptor—specifically interacting with the NR2A subunit—and acts as an inhibitor of NMDA receptor activity in rat cortical neurons. There are no approved indications or clinical trials reported for this molecule; it is primarily used in research settings to study NMDA receptor pharmacology[1][6].
- Other names
- 1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-(4-methoxyphenyl)sulfonylpiperazinePiperazine, 1-[(2,3-dihydro-1,4-benzodioxin-6-yl)sulfonyl]-4-[(4-methoxyphenyl)sulfonyl]-
02
Targets
GRIN2A (NMDA receptor subunit 2A)
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